Homes for Sale in Scott City, MO (63780)

Browse every active MARIS IDX listing in Scott City, MO (zip code 63780). Updated every 15 minutes from MLS Grid. Currently showing 28 active IDX listings.

28 active listings updated every 5 minutes

Featured Listings

00 E Outer Road, Lot 1, Scott City, MO, 63780
Active
MLS#26018314

$3,169,425

00 E Outer Road, Lot 1, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

The SEMO Industrial Park offers 380 acres of ready-to-go land subdivided into lots ranging from 5 to 20 acres, perfect for businesses of all sizes. The park is...

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2477 State Highway E, Scott City, MO, 63780
Active
MLS#26062589

$309,900

2477 State Highway E, Scott City, MO, 63780

  • 3 Bed

  • 3 Bath

  • 3,124 Sqft

4.03 acres located out of city limits with large detached shop & attached garage. Updates in the last 3 years include roof, septic, windows, heat & air, deck,...

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3141 E Outer Road, Scott City, MO, 63780
Active
MLS#26013998

$4,200,000

3141 E Outer Road, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Positioned along Interstate 55 in Scott City, this rare 5-acre industrial outdoor storage (IOS) facility offers a turnkey opportunity for fleet, equipment, or s...

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3141 E Outer Road, Scott City, MO, 63780
Active
MLS#26013966

$450,000

3141 E Outer Road, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Prime 2.6-acre property with all city utilities and services readily available. The gravelled, fenced lot with highway sign availability provides the perfect f...

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881 Scott Street, Scott City, MO, 63780
Active
MLS#26007662

$209,000

881 Scott Street, Scott City, MO, 63780

  • 3 Bed

  • 2 Bath

  • 0 Sqft

Brand new construction in Scott City! This 3-bedroom, 2-bath home offers 1,140 sq ft of stylish, low-maintenance living with stained concrete floors throughout...

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136 N 6th Street, Sikeston, MO, 63780
Active
MLS#25039657

$44,900

136 N 6th Street, Sikeston, MO, 63780

  • 2 Bed

  • 2 Bath

  • 576 Sqft

Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you...

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1705 Main Street, Scott City, MO, 63780
Active
MLS#26046694

$239,900

1705 Main Street, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Prime commercial property designed for retail/vehicle related uses or distribution uses. Boasting 4,780 SF of modern space, including 1,250 SF of office area, t...

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105 Druetta Avenue, Scott City, MO, 63780
Active
MLS#26060521

$41,000

105 Druetta Avenue, Scott City, MO, 63780

  • 3 Bed

  • 1 Bath

  • 1,025 Sqft

This home is a great buy. 3BR, 1 bath ranch home, i car attached garage and level back yard.

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519 Natchez Trace, Scott City, MO, 63780
Active
MLS#25066722

$90,000

519 Natchez Trace, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Imagine waking up to breathtaking views of the mighty Mississippi River every single day! This rare 1.63 acre level lot is perfectly positioned in one of Scott...

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31 SEMO Industrial Park, Lot 31, Scott City, MO, 63780
Active
MLS#26018647

$607,662

31 SEMO Industrial Park, Lot 31, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

The SEMO Industrial Park offers 380 acres of ready-to-go land subdivided into lots ranging from 5 to 20 acres, perfect for businesses of all sizes. The park is...

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5 SEMO Industrial Park, Lot 5, Scott City, MO, 63780
Active
MLS#26018540

$526,640

5 SEMO Industrial Park, Lot 5, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

The SEMO Industrial Park offers 380 acres of ready-to-go land subdivided into lots ranging from 5 to 20 acres, perfect for businesses of all sizes. The park is...

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116 E Missouri Boulevard, Scott City, MO, 63780
Active
MLS#26018851

$435,000

410 Main Street, Scott City, MO, 63780
Active
MLS#26028295

$290,000

410 Main Street, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

This prime commercial property offers an industrial 3,720 SF building that includes an office/waiting area, restroom, six convenient overhead drive-in doors, an...

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18 SEMO Industrial Park, Lot 18, Scott City, MO, 63780
Active
MLS#26018659

$2,001,255

18 SEMO Industrial Park, Lot 18, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

The SEMO Industrial Park offers 380 acres of ready-to-go land subdivided into lots ranging from 5 to 20 acres, perfect for businesses of all sizes. The park is...

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0 E Outer Road, Scott City, MO, 63780
Active
MLS#26014100

$425,000

0 E Outer Road, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

5.27 acre site-ready commercial tract offers unparalleled visibility along Interstate 55. Boasting frontage on both the East Outer Road and Rock Levee Road, as...

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3046 Nash Road, Scott City, MO, 63780
Active
MLS#26012668

$1,480,000

3046 Nash Road, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

This prime industrial property features a recently constructed 10,400 SF building, with a 2,400 SF high-quality office area and an 8,000 SF shop/warehouse boast...

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11001 State Route N, Unincorporated, MO, 63780
Active
MLS#26019853

$1,500,000

11001 State Route N, Unincorporated, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Introducing a great business opportunity with real estate in Scott City, MO! Discover the natural beauty of Southeast Missouri at Amor on the River, a premier...

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1880 Mary Street, Scott City, MO, 63780
Active
MLS#25058657

$189,500

1880 Mary Street, Scott City, MO, 63780

  • 3 Bed

  • 3 Bath

  • 1,830 Sqft

Searching for a three bedroom ranch style home with fresh paint, new kitchen cabinets and updated butcher block countertops, then step right in and you will fin...

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4930 Nash Road, Scott City, MO, 63780
Active
MLS#26012464

$2,200,000

4930 Nash Road, Scott City, MO, 63780

  • 0 Bed

  • 0 Bath

  • 0 Sqft

4930 Nash Rd offers a 21,600 SF property designed for efficiency and productivity. This expansive site encompasses a 7,200 SF office and warehouse building, a 4...

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1515 Mary Street, Scott City, MO, 63780
Active
MLS#26057190

$249,900

1515 Mary Street, Scott City, MO, 63780

  • 3 Bed

  • 2 Bath

  • 1,587 Sqft

This charming 1,587 sq ft ranch, built by a trusted local builder, perfectly combines style and practicality. With a split bedroom layout, it features 3 bedroom...

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218 Lula Avenue, Scott City, MO, 63780
Active
MLS#26051771

$79,000

218 Lula Avenue, Scott City, MO, 63780

  • 3 Bed

  • 1 Bath

  • 977 Sqft

Step into the charm and simplicity of this 3-bedroom ranch nestled in a quiet Scott City neighborhood! Built in 1910 and situated on a spacious 10,454 sq ft cor...

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1911 Yale Drive, Scott City, MO, 63780
Active
MLS#25074316

$153,900

1911 Yale Drive, Scott City, MO, 63780

  • 3 Bed

  • 2 Bath

  • 1,388 Sqft

Charming 3-Bedroom Home in Country Club Estates Welcome to 1911 Yale, Scott City, MO 63780! This 3-bedroom, 2-bathroom home is tucked into the desirable 2nd...

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28550 US Highway 61, Scott City, MO, 63780
Active Under Contract
MLS#26060853

$225,000

28550 US Highway 61, Scott City, MO, 63780

  • 3 Bed

  • 1 Bath

  • 1,163 Sqft

The unicorn property! This 3 bedroom, 1 bathroom home with a garage located in Scott City sits quietly on just over 6 acres! You saw that right- enjoy the land...

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85 Logan Lane, Scott City, MO, 63780
Active Under Contract
MLS#26048123

$221,900

85 Logan Lane, Scott City, MO, 63780

  • 3 Bed

  • 2 Bath

  • 1,820 Sqft

Tucked away on 2 beautiful acres, this 3-bedroom, 2-bath home offers the peace and privacy that's becoming harder to find. Surrounded by nature, you'll enjoy ro...

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About Scott City, MO (63780)

Scott City in unincorporated Scott County sits roughly 20-25 minutes south of downtown St. Louis, offering a semi-rural setting with reasonable commute access to the city. The area has a quiet, small-town character with a mix of established residential neighborhoods and open land, making it appealing to buyers seeking more space and lower density than suburban alternatives. Properties here range from modest older homes to significant acreage and newer construction, attracting both primary residence buyers and investors looking for value.

Buyers in 63780 should be aware that unincorporated status means county services handle zoning, code enforcement, and utilities—which can vary by location. Many properties have well and septic systems rather than municipal service, so due diligence on those systems is important during inspection.

Market Overview

The 63780 zip code currently shows 23 active and coming-soon listings with prices ranging from $11,200 to $4,200,000, reflecting significant diversity in property type and condition. The market includes everything from fixer-uppers and vacant land to established homes and larger residential estates, with buyers ranging from first-time investors to those seeking rural or semi-rural living with land. Typical transactions involve either investors targeting renovation opportunities or families drawn by affordable entry prices and more acreage than comparable properties closer to the city.

Schools

Schools in this area include several districts within Scott County—check with the listing agent for the specific school assignment for any address.

Neighborhoods & Subdivisions

Current listings in 63780 appear across multiple established and historic subdivisions, including Schuettes Add, Murphy & Walls Addition, Murphy & Walls 2nd Add, Berkley Acres James Outlot, Wells Add, Country Club, Leos Add, Parkwood 2nd ADDN, and Dohognes 1st Add, along with some unsubdivided residential parcels. These neighborhoods reflect the area's mixed development pattern over several decades, ranging from older platted additions to more modern residential sections.

About Scott County

Zip code 63780 is located in Scott County. Refine your search by price, beds, baths and more using the filters above the listings grid.

Communities and Cities Within

Local agents who actually know Scott City, MO (63780)

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