Homes for Sale in Defiance, MO (63341)

Browse every active MARIS IDX listing in Defiance, MO (zip code 63341). Updated every 15 minutes from MLS Grid. Currently showing 47 active IDX listings.

47 active listings updated every 5 minutes

Featured Listings

 4 Wolf Trail Court, Unincorporated, MO, 63341
Coming Soon
MLS#26062828

$615,000

4 Wolf Trail Court, Unincorporated, MO, 63341

  • 4 Bed

  • 2 Bath

  • 2,364 Sqft

Welcome to this spacious and thoughtfully designed 4-bedroom, 2 bath home offering numerous updates and plenty of flexible living space. The main level features...

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2275 Highway F, LOT 1, Unincorporated, MO, 63341
Active
MLS#26053202

$3,450,000

2275 Highway F, LOT 1, Unincorporated, MO, 63341

  • 5 Bed

  • 4 Bath

  • 2,815 Sqft

Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son N...

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215 Rugged Acres, Unincorporated, MO, 63341
Active
MLS#26053227

$639,000

215 Rugged Acres, Unincorporated, MO, 63341

  • 3 Bed

  • 2 Bath

  • 2,013 Sqft

Experience peaceful country living in this stunning 2- year old ranch home nestled on 5 mostly wooded, unrestricted acres in the picturesque Femme Osage Valley....

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2 Patrick Lane, Unincorporated, MO, 63341
Active
MLS#26054878

$750,000

2 Patrick Lane, Unincorporated, MO, 63341

  • 4 Bed

  • 4 Bath

  • 4,044 Sqft

SPACE, ACREAGE & GARAGE GALORE! Nestled on just over 3 acres in desirable Defiance, this expansive 1.5-story home offers abundant living space, updates & the fl...

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2323 Highway F, LOT 3, Unincorporated, MO, 63341
Active
MLS#26053360

$1,899,900

2323 Highway F, LOT 3, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Imagine owning a piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son Nathan and...

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2275 Highway F, Unincorporated, MO, 63341
Active
MLS#26057899

$7,748,800

2275 Highway F, Unincorporated, MO, 63341

  • 5 Bed

  • 4 Bath

  • 2,815 Sqft

Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son N...

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300B Callaway Ridge Drive, Unincorporated, MO, 63341
Active
MLS#25072442

$650,000

300B Callaway Ridge Drive, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Discover your private oasis on this rare 28.1-acre parcel in the sought-after Callaway Valley Subdivision! Perfect for your dream home or personal estate, this...

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8 Whippoorwill Court, Unincorporated, MO, 63341
Active
MLS#26045108

$549,900

8 Whippoorwill Court, Unincorporated, MO, 63341

  • 4 Bed

  • 4 Bath

  • 3,057 Sqft

Escape to your own private retreat with this stunning log home nestled on 3 ACRES, where peaceful country living meets modern comfort. Surrounded by mature tree...

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510 Callaway Estates Drive, Unincorporated, MO, 63341
Active
MLS#26020025

$350,000

510 Callaway Estates Drive, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded...

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19 Greenview Drive, Unincorporated, MO, 63341
Active
MLS#26057258

$599,900

19 Greenview Drive, Unincorporated, MO, 63341

  • 3 Bed

  • 3 Bath

  • 1,935 Sqft

NEW PRICE! Stunning, Incredible views in the home located in the beautiful community of Callaway Farms! This open and inviting home is a rare find! The style i...

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4 Cooper's Court, Unincorporated, MO, 63341
Active
MLS#26020042

$587,000

4 Cooper's Court, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded...

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0 Defiance Road, Unincorporated, MO, 63341
Active
MLS#26025560

$375,000

0 Defiance Road, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

8.5+/- Fabulous acres that offer a combination of open land, level to rolling hills, wooded land & access to a shared pond. Rare opportunity to own this beautif...

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3840 Rooster Ridge Lane, Unincorporated, MO, 63341
Active
MLS#26055828

$699,900

3840 Rooster Ridge Lane, Unincorporated, MO, 63341

  • 3 Bed

  • 4 Bath

  • 5,601 Sqft

Welcome to your own private retreat! Nestled on 3 beautiful acres with peaceful wooded views, this stunning 3-bedroom, 3.5-bath home offers the perfect blend of...

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104 Wolf Trail Court, Unincorporated, MO, 63341
Active
MLS#26062370

$819,900

104 Wolf Trail Court, Unincorporated, MO, 63341

  • 4 Bed

  • 4 Bath

  • 4,937 Sqft

Great opportunity in a desirable Defiance location! This home offers the chance to add your own style and build equity with some updating and a little vision. S...

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5001 Lily Ridge, Unincorporated, MO, 63341
Active
MLS#25049001

$279,900

5001 Lily Ridge, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Four Luxurious home sites, on 5 acre lots. Sunset Estates in St. Charles County MO. Located in the heart of Defiance and wine country. Bring your own builder/...

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220 Northlind Drive, Unincorporated, MO, 63341
Active
MLS#26037028

$1,400,000

220 Northlind Drive, Unincorporated, MO, 63341

  • 5 Bed

  • 7 Bath

  • 6,521 Sqft

Stunning brick and stone ranch-style home sitting on 3 private acres surrounded by mature trees and scenic views! This custom-built home boasts 5 bedrooms, 4 fu...

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5011 Lily Ridge, Unincorporated, MO, 63341
Active
MLS#25047178

$279,900

5011 Lily Ridge, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder...

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0 Callaway Ridge Drive, Unincorporated, MO, 63341
Active
MLS#26057013

$899,946

0 Callaway Ridge Drive, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

This 29.9 acre parcel is an incredible opportunity to purchase your dream property to build your dream house or even as a land bank. The housing in area is abso...

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3901 Highway D, Unincorporated, MO, 63341
Active
MLS#26041787

$364,950

3901 Highway D, Unincorporated, MO, 63341

  • 3 Bed

  • 1 Bath

  • 1,296 Sqft

Ranch style, full brick home situated on 4.6 acres with an attached one car garage. The home has 3 bedrooms, 1 bath, 1296 square feet, some hardwood floors, and...

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44 Wilderness Lane, Unincorporated, MO, 63341
Active
MLS#26042478

$600,000

44 Wilderness Lane, Unincorporated, MO, 63341

  • 4 Bed

  • 3 Bath

  • 3,000 Sqft

RARE DEFIANCE ACREAGE OPPORTUNITY! Tucked away at the end of a peaceful cul-de-sac, this 4-bedroom, 2.5-bath home offers approximately 3,000 sq. ft. of finished...

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85 Mar Len Drive, Unincorporated, MO, 63341
Active
MLS#26053053

$650,000

85 Mar Len Drive, Unincorporated, MO, 63341

  • 3 Bed

  • 3 Bath

  • 3,730 Sqft

Tucked away on 4.75 beautiful acres surrounded by mature trees, this charming 3-bedroom, 3-bath home offers the perfect blend of privacy, space, and outdoor liv...

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29 Greenview Drive, Unincorporated, MO, 63341
Active
MLS#26053250

$665,999

29 Greenview Drive, Unincorporated, MO, 63341

  • 4 Bed

  • 4 Bath

  • 4,025 Sqft

Set on 9.5 wooded acres, this meticulously maintained 4 bedroom, 4 bath ranch offers the kind of privacy and quiet that is getting harder to find. No traffic no...

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110 Steeple Point Dr. Lot # 14 Drive, Unincorporated, MO, 63341
Active
MLS#25080614

$238,900

110 Steeple Point Dr. Lot # 14 Drive, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

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120 Steeple Point Dr. Lot #13 Drive, Unincorporated, MO, 63341
Active
MLS#25080484

$152,000

120 Steeple Point Dr. Lot #13 Drive, Unincorporated, MO, 63341

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

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See All Homes for Sale in Defiance, MO (63341) →

About Defiance, MO (63341)

Zip code 63341 is located in unincorporated St. Charles County, positioned in the outer suburbs northwest of St. Louis. This area offers a more rural and spacious feel compared to closer-in suburban communities, with larger lots and a quieter character that appeals to buyers seeking country living while remaining within commuting distance of the metro area.

The unincorporated nature of 63341 means residents aren't bound to a specific municipality, which can mean less restrictive zoning and more flexibility for property development. Buyers here typically value privacy, acreage, and a slower pace of life, though they should be aware that unincorporated areas may have different utility options and service patterns than incorporated towns.

Market Overview

The 63341 housing market currently shows 41 active and coming-soon listings with prices ranging from $75,000 to $4,422,000, reflecting a diverse inventory that spans from affordable properties to luxury estates. The market here tends to feature a mix of rural residential properties, hobby farms, and larger estate homes, often appealing to buyers looking for land and space rather than density. Sellers in this zip code should expect a buyer base prioritizing acreage, privacy, and country character over urban convenience.

Schools

Schools in this area include several districts within St Charles County -- check with the listing agent for the specific school assignment for any address.

Neighborhoods & Subdivisions

Current listings in 63341 are located in and around several neighborhoods and subdivisions including Callaway Valley, Callaway Farms, Indian Ridge Farms, Crown Pointe Farms, Lakeway, Saddleback, Wilderness, Country Oaks, and other established residential communities that reflect the area's rural and semi-rural character.

About St Charles County

Zip code 63341 is located in St Charles County. Refine your search by price, beds, baths and more using the filters above the listings grid.

Communities and Cities Within

Defiance

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