Unique opportunity to acquire a substantial downtown flex-industrial headquarters facility totaling 19,498 square feet on nearly one acre in the heart of Sikeston. The offering includes three parcels, including two additional parcels providing valuable off-street parking and expansion flexibility. Designed to support both administrative and operational functions, the property features approximately 8,000 square feet of office space complemented by approximately 11,000 square feet of warehouse and operational space. The office component includes numerous private offices, conference rooms, collaborative work areas, and support spaces capable of accommodating executive, management, sales, customer service, and administrative teams under one roof. The warehouse portion serves as the operational backbone of the facility, extending the full length of the building and providing rare drive-through access between two city streets via overhead doors on both ends. This unique layout creates exceptional efficiencies for fleet operations, equipment storage, distribution, logistics, contractors, service providers, and light industrial users. Properties offering this combination of office infrastructure, operational capacity, parking, and strategic location are increasingly difficult to find. Whether serving as a corporate headquarters, regional operations center, service hub, logistics facility, or owner-occupied investment, 205 S New Madrid Street offers the scale, flexibility, and functionality to support long-term business growth.
0 Bed
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$0 per sq.ft
$ 449,500
Active
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26038113
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Trotters Add
Scott
Commercial Sale
Commercial Sale
$9,839
Last 6 closed homes in this zip.
| Address | Bd/Ba | SqFt | List | Sold | Closed |
|---|---|---|---|---|---|
| 1208 Huntress Drive, Sikeston, MO 63801 | 3/2 | 1,884 | $325,000 | $320,000 98.5% of ask |
Aug 28, 2026 |
| 1789 State Highway Z, Sikeston, MO 63801 | 3/2 | 2,059 | $385,000 | $372,500 96.8% of ask |
Aug 28, 2026 |
| 210 Sherrie Drive, Sikeston, MO 63801 | 3/2 | 2,121 | $249,900 | $249,900 100% of ask |
Aug 28, 2026 |
| 170 Lee Avenue, Sikeston, MO 63801 | 3/1 | 875 | $60,000 | $51,000 85% of ask |
Aug 25, 2026 |
| 921 Bucklin Circle, Sikeston, MO 63801 | 3/2 | 1,701 | $245,000 | $257,875 105.3% of ask |
Aug 25, 2026 |
| 166 Cypress Drive, Sikeston, MO 63801 | 3/2 | 1,400 | $220,000 | $218,500 99.3% of ask |
Aug 24, 2026 |
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