Homes for Sale in Pilot Knob, MO (63663)

Browse every active MARIS IDX listing in Pilot Knob, MO (zip code 63663). Updated every 15 minutes from MLS Grid. Currently showing 9 active IDX listings.

9 active listings updated every 5 minutes

Featured Listings

 500 N Saint Mary Street, Pilot Knob, MO, 63663
Active
MLS#24066469

$600,000

500 N Saint Mary Street, Pilot Knob, MO, 63663

  • 0 Bed

  • 0 Bath

  • 40,096 Sqft
  • 709
    Days

Great Investment Opportunity sitting on 6.8 acres m/l with an open canvas to do want you want with. Located perfectly off the highway with easy access to the gr...

View Details
221 HWY Vance Rd, Old Middlebrook Rd, 221 Hwy, Ironton, MO, 63663
Active
MLS#26006032

$2,747,500

221 HWY Vance Rd, Old Middlebrook Rd, 221 Hwy, Ironton, MO, 63663

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Discover this exceptional 785+/- acre tract spanning St. Francois County and Iron County, offering a rare opportunity to own a large, contiguous piece of the Mi...

View Details
103 Bogy, Pilot Knob, MO, 63663
Active
MLS#26054339

$12,900

103 Bogy, Pilot Knob, MO, 63663

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Prime Development Opportunity in the Heart of Arcadia Valley! Discover an exceptional opportunity to own a vacant city lot in the heart of beautiful Pilot Knob...

View Details
309 North Lucas, Pilot Knob, MO, 63663
Active
MLS#26054350

$160,000

309 North Lucas, Pilot Knob, MO, 63663

  • 2 Bed

  • 1 Bath

  • 0 Sqft

Duplex with 2 Bedrooms. Covered parking and solid renters.

View Details
211 Maple St, Pilot Knob, MO, 63663
Active
MLS#26022223

$199,900

211 Maple St, Pilot Knob, MO, 63663

  • 3 Bed

  • 2 Bath

  • 1,620 Sqft

Take a look at this charming new construction 3- bedroom, 2 bath home featuring a spacious open-concept floor plan designed for comfortable living and entertain...

View Details
586 St Marys Street, 566-651, Pilot Knob, MO, 63663
Active
MLS#26043543

$2,750,000

586 St Marys Street, 566-651, Pilot Knob, MO, 63663

  • 0 Bed

  • 0 Bath

  • 0 Sqft

50 UNIT APARTMENT COMPLEX IN ARCADIA VALLEY Rare opportunity to acquire a 50-unit multifamily portfolio in Arcadia Valley, Missouri one of Southeast Missouri's’...

View Details
208 N Valle Street, Pilot Knob, MO, 63663
Active
MLS#26052646

$132,900

208 N Valle Street, Pilot Knob, MO, 63663

  • 3 Bed

  • 2 Bath

  • 1,408 Sqft

Charming, home in the heart of Pilot Knob! This spacious 3-bedroom, 2-bath home offers approximately 1,408± sq. ft. of comfortable living space with an inv...

View Details
310 N McCune, Pilot Knob, MO, 63663
Active
MLS#25029985

$1,075,000

310 N McCune, Pilot Knob, MO, 63663

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Charming Hotel in the Heart of Missouri’s Beautiful Arcadia Valley! Location, History & Adventure — All in One Investment! Nestled in scenic Arcadia Valley, thi...

View Details
202 N McCune Street, Pilot Knob, MO, 63663
Active
MLS#25073490

$430,000

202 N McCune Street, Pilot Knob, MO, 63663

  • 0 Bed

  • 0 Bath

  • 0 Sqft

Exceptional investment or redevelopment opportunity on a prime 0.74 acre corner lot this well-known former lumberyard features excellent visibility high traffic...

View Details
See All Homes for Sale in Pilot Knob, MO (63663) →

About Pilot Knob, MO (63663)

Pilot Knob is located in Iron County in southeastern Missouri, roughly 60-70 miles south of St. Louis in the heart of the Ozark region. The area is characterized by a mix of rural and small-town living, with a strong connection to the region's mining heritage and natural landscape. Buyers relocating here should expect a quieter, more spacious lifestyle compared to urban St. Louis, with properties ranging from modest homes to larger estates on acreage.

The community offers access to outdoor recreation and a close-knit neighborhood feel, though amenities and services are more limited than suburban areas closer to the city. This zip code appeals to buyers seeking affordable land and homes, retirees, or those who work remotely and value the slower pace of southeastern Missouri.

Market Overview

The 63663 zip code housing market is affordable and diverse, with current listings ranging from $150,000 to $2,750,000. The market is dominated by single-family homes on varying lot sizes, from modest starter homes to significant properties with acreage. Typical sellers are relocating out of the area or downsizing, while buyers are often attracted by affordability, land availability, and the rural lifestyle.

Schools

Schools in this area include several districts within Iron County -- check with the listing agent for the specific school assignment for any address.

Neighborhoods & Subdivisions

Residential areas in 63663 include established neighborhoods and subdivisions such as Grittiyas Acres Subdivision, Fort Davidson Heights Subdivision, Morningside Acres Subdivision, and the McCune and Murdock Crumb areas, along with homes throughout the city of Pilot Knob itself. These neighborhoods range from small rural subdivisions to scattered homes on larger tracts of land.

About Iron County

Zip code 63663 is located in Iron County. Refine your search by price, beds, baths and more using the filters above the listings grid.

Communities and Cities Within

Pilot Knob

Local agents who actually know Pilot Knob, MO (63663)

StLouisRealEstate.com is run by Guerrilla Brokers, LLC -- a locally owned brokerage serving the St Louis region. When you reach out from a listing, you talk to a local REALTOR ®, not a national call center.

Call 866.STL.MLS1
StLouisRealEstate.com The authoritative site for all things St. Louis real estate
Homes for Sale by Area
Thinking of Selling
Property Types

Disclaimer: Listings courtesy of MARIS MLS as distributed by MLS GRID. The information on this site is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The information contained herein is deemed reliable but is not guaranteed by MLS GRID, MARIS, Guerrilla Brokers, LLC or the owner of this website. The listing information shown herein is based on information submitted to the MLS GRID as of 10/02/2026 12:15 PM. All data is obtained from various sources and may not have been verified by MLS GRID, MARIS, Guerrilla Brokers, LLC or the owner of this website. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

© 2026 StLouisRealEstate.com · Guerrilla Brokers, LLC. All rights reserved.