Homes for Sale in Fredericktown, MO (63645)

Browse every active MARIS IDX listing in Fredericktown, MO (zip code 63645). Updated every 15 minutes from MLS Grid. Currently showing 56 active IDX listings.

56 active listings updated every 15 minutes

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 1226 S Deer Trail, Fredericktown, MO, 63645 - 4 bed, 3 bath home for sale in Fredericktown, MO

$485,000

180 days on market
1226 S Deer Trail, Fredericktown, MO, 63645
4bd | 3ba | 1,740sqft |$279/sqft |180 DOM |1 Story MLS#26029168
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905 High Street, Cobalt, MO, 63645 - 3 bed, 1 bath home for sale in Fredericktown, MO

$99,900

22 days on market
905 High Street, Cobalt, MO, 63645
3bd | 1ba | 1,038sqft |$96/sqft |22 DOM |1 Story MLS#26068009
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1515 Madison 404, Unincorporated, MO, 63645 - 3 bed, 3 bath home for sale in Fredericktown, MO

$338,000

Price drop $27,000 was $365,000
1515 Madison 404, Unincorporated, MO, 63645
3bd | 3ba | 1,934sqft |$175/sqft |149 DOM |1.5 Story MLS#26037204
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1251 S Deer Trail, Fredericktown, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$210,000

Price drop $10,000 was $220,000
1251 S Deer Trail, Fredericktown, MO, 63645
3bd | 2ba | 1,600sqft |$131/sqft |84 DOM |1 Story MLS#26052470
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706 High Street, Fredericktown, MO, 63645 - 2 bed, 1 bath home for sale in Fredericktown, MO

$149,900

12 days on market
706 High Street, Fredericktown, MO, 63645
2bd | 1ba | 834sqft |$180/sqft |12 DOM |1 Story MLS#26069492
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309 Franklin St, Fredericktown, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$184,900

Price drop $5,100 was $190,000
309 Franklin St, Fredericktown, MO, 63645
3bd | 2ba | 1,367sqft |$135/sqft |54 DOM |1 Story MLS#26060978
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1350 White Tail Drive, Cobalt, MO, 63645 - 3 bed, 3 bath home for sale in Fredericktown, MO

$384,999

14 days on market
1350 White Tail Drive, Cobalt, MO, 63645
3bd | 3ba | 1,678sqft |$229/sqft |14 DOM |1 Story MLS#26068664
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308 Cahoon Street, Fredericktown, MO, 63645 - 2 bed, 1 bath home for sale in Fredericktown, MO

$79,999

5 days on market
308 Cahoon Street, Fredericktown, MO, 63645
2bd | 1ba | 896sqft |$89/sqft |5 DOM |1 Story MLS#26071522
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6004 Highway 67, Fredericktown, MO, 63645 - 4 bed, 2 bath home for sale in Fredericktown, MO

$299,000

18 days on market
6004 Highway 67, Fredericktown, MO, 63645
4bd | 2ba | 2,336sqft |$128/sqft |18 DOM |1.5 Story MLS#26068857
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7 Ivy Lane, Unincorporated, MO, 63645 - 0 bed, 0 bath home for sale in Fredericktown, MO

$229,999

152 days on market
7 Ivy Lane, Unincorporated, MO, 63645
1,478sqft |$156/sqft |152 DOM |1 Story MLS#26037968
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907 Marlowe Street, Cobalt, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$199,900

Price drop $10,000 was $209,900
907 Marlowe Street, Cobalt, MO, 63645
3bd | 2ba | 1,100sqft |$182/sqft |44 DOM |1 Story MLS#26063013
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2049 Madison 208, Fredericktown, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$415,000

Price drop $10,000 was $425,000
2049 Madison 208, Fredericktown, MO, 63645
3bd | 2ba | 1,910sqft |$217/sqft |173 DOM |Multi/Split MLS#26013121
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5413 State Highway 72, Unincorporated, MO, 63645 - 4 bed, 2 bath home for sale in Fredericktown, MO

$219,000

8 days on market
5413 State Highway 72, Unincorporated, MO, 63645
4bd | 2ba | 1,430sqft |$153/sqft |8 DOM |1 Story MLS#26069968
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112 Village Creek Road, Fredericktown, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$220,000

Price drop $5,000 was $225,000
112 Village Creek Road, Fredericktown, MO, 63645
3bd | 2ba | 1,868sqft |$118/sqft |107 DOM |Multi/Split MLS#26048243
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1872 Madison 219, Unincorporated, MO, 63645 - 5 bed, 3 bath home for sale in Fredericktown, MO

$439,500

5 days on market
1872 Madison 219, Unincorporated, MO, 63645
5bd | 3ba | 1,166sqft |$377/sqft |5 DOM |1 Story MLS#26070181
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1126 S Deer Trail, Fredericktown, MO, 63645 - 4 bed, 3 bath home for sale in Fredericktown, MO

$254,888

156 days on market
1126 S Deer Trail, Fredericktown, MO, 63645
4bd | 3ba | 1,068sqft |$239/sqft |156 DOM |1 Story MLS#26037019
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607 South Wood Avenue, Fredericktown, MO, 63645 - 5 bed, 2 bath home for sale in Fredericktown, MO

$179,900

Price drop $15,000 was $194,900
607 South Wood Avenue, Fredericktown, MO, 63645
5bd | 2ba | 1,554sqft |$116/sqft |78 DOM |1 Story MLS#26055580
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13907 #2 Highway T, Other, MO, 63645 - 5 bed, 5 bath home for sale in Other, MO

$484,900

Price drop $9,600 was $494,500
13907 #2 Highway T, Other, MO, 63645
5bd | 5ba | 3,980sqft |$122/sqft |296 DOM |1 Story MLS#26004131
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8076 T Highway, Fredericktown, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$375,000

28 days on market
8076 T Highway, Fredericktown, MO, 63645
3bd | 2ba | 1,260sqft |$298/sqft |28 DOM |1 Story MLS#26066669
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1433 Madison 9558, Fredericktown, MO, 63645 - 2 bed, 1 bath home for sale in Fredericktown, MO

$174,900

2 days on market
1433 Madison 9558, Fredericktown, MO, 63645
2bd | 1ba | 903sqft |$194/sqft |2 DOM |1 Story MLS#26072102
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6186 Highway, Fredericktown, MO, 63645 - 3 bed, 2 bath home for sale in Fredericktown, MO

$265,000

Price drop $35,000 was $300,000
6186 Highway, Fredericktown, MO, 63645
3bd | 2ba | 1,792sqft |$148/sqft |63 DOM |1 Story MLS#26059087
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318 Loughborough Street, Fredericktown, MO, 63645 - 2 bed, 1 bath home for sale in Fredericktown, MO

$169,900

51 days on market
318 Loughborough Street, Fredericktown, MO, 63645
2bd | 1ba | 960sqft |$177/sqft |51 DOM |1 Story MLS#26058873
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409 Matthews Street, Fredericktown, MO, 63645 - 3 bed, 1 bath home for sale in Fredericktown, MO

$139,999

8 days on market
409 Matthews Street, Fredericktown, MO, 63645
3bd | 1ba | 1,008sqft |$139/sqft |8 DOM |1 Story MLS#26070210
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404 Marshall Street, Fredericktown, MO, 63645 - 4 bed, 4 bath home for sale in Fredericktown, MO

$239,900

Price drop $10,000 was $249,900
404 Marshall Street, Fredericktown, MO, 63645
4bd | 4ba | 2,748sqft |$87/sqft |257 DOM |2 Story MLS#26008245
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About Fredericktown, MO (63645)

Zip code 63645 encompasses Womack and surrounding unincorporated areas in Ste. Genevieve County, located in the heart of Missouri's rolling countryside roughly 60–70 miles south of St. Louis. This is classic rural Missouri terrain, characterized by farmland, wooded hills, and a quiet, small-town pace that appeals to buyers seeking distance from urban congestion while still maintaining reasonable access to regional amenities.

Buyers relocating to 63645 should expect a genuinely rural setting with larger lot sizes, privacy, and a strong sense of community rooted in agriculture and local history. Infrastructure and services are more limited than in suburban St. Louis counties, so commuters and those requiring frequent urban amenities will want to factor in drive times and plan accordingly.

Market Overview

The 63645 housing market spans a wide price range from $5,000 to $2,520,000, reflecting everything from vacant land and fixer-uppers to substantial rural estates and hobby farms. Most active listings tend toward rural homes on acreage, land parcels, and country properties rather than tight suburban subdivisions, attracting both lifestyle buyers and investors interested in agricultural or development potential.

Schools

Schools in this area include several districts within Ste. Genevieve County—check with the listing agent for the specific school assignment for any address.

Neighborhoods & Subdivisions

Neighborhoods and subdivisions in 63645 include Cooks Add, Pine Castle Estates, Buford Heights, Rural Madison County, Newman Lake, Graham, Hillcrest, and the City Limits of Frederick Town, along with scattered rural properties outside any formal subdivision.

About Madison County

Zip code 63645 is located in Madison County. Refine your search by price, beds, baths and more using the filters above the listings grid.

Communities and Cities Within

Fredericktown

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Disclaimer: Listings courtesy of MARIS MLS as distributed by MLS GRID. The information on this site is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The information contained herein is deemed reliable but is not guaranteed by MLS GRID, MARIS, Missouri Online Real Estate, Inc. or the owner of this website. The listing information shown herein is based on information submitted to the MLS GRID as of 11/14/2026 04:15 AM CT. All data is obtained from various sources and may not have been verified by MLS GRID, MARIS, Missouri Online Real Estate, Inc. or the owner of this website. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

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